• Suboxone treatment

The Perils of Ingesting Other Harmful Substances with Suboxone

Using Suboxone for the long term can cause some complications in the human body. According to the experts at suboxone treatment centers, the side effects of this medication’s long-term use are many, including nausea and intense bouts of anxiety and depression. However, inappropriate use of this medication can also cause immediate complications.

According to SAMHSA (The Substance Abuse and Mental Health Services Administration), a significant number of patients are admitted to the hospitals due to buprenorphine-related overdoses. A high percentage of this volume of patients is accepted because of the complications resulting from the ingestion of buprenorphine with other illicit or harmful substances. 

Suboxone treatment has many benefits, but using it appropriately to prevent the outbreak of severe complications is of great significance.  

The working of Suboxone 

Suboxone = Buprenorphine + Naloxone. 

Buprenorphine, a partial opioid agonist, binds to those receptors in your brain that the opiates like oxycodone, heroin, etc., bind to. But, fortunately, the effects that buprenorphine produces are not similar to the ones produced by opiates. In simpler words, individuals who have developed an opiate dependency will not feel the same “high” from buprenorphine that they experience from opiates.

However, the receptors in their brain are tricked into believing that they are consuming opiates. It prevents individuals from experiencing withdrawals associated with opiates like heroin, oxycodone, etc. 

According to the DEA (The United States Drug Enforcement Administration), buprenorphine is a Schedule III controlled substance, which means that it has a potential for abuse; a person can develop physical dependence. Therefore, in Suboxone, naloxone is combined with buprenorphine.  

The suboxone doctors near me inform me that naloxone is an opiate antagonist. It does not allow opiates to attach to the receptors in our brain. If an individual tries to abuse Suboxone to get “high,” the naloxone present in it will knock the buprenorphine off the opiate receptors in the brain, preventing the “high.” Once naloxone is activated, the individual will experience opiate withdrawal symptoms. 

Suboxone is technically an opioid drug. Therefore, taking it with other harmful substances like alcohol, benzodiazepines, cocaine, etc., can have severe implications on the human body.  

Harmful Interactions 

Suboxone with Benzodiazepines

Benzos, or benzodiazepines, belong to a class of drugs that depresses the central nervous system. Benzos are primarily prescribed to treat anxiety and insomnia, but they can treat many other conditions as well. According to the professionals at sublocade treatment centers, these depressants are most commonly prescribed in the US. 

Short-term effects of benzos include: 



Vision problems

Impaired motor function




Respiratory depression 

Long-term effects of benzos include: 

Issues with judgment and memory

Physical weakness

Confusion or disorientation 

Higher doses of benzos can slow down reflexes, cause mood alterations, erratic behavior and thinking, and a euphoric state. Mixing benzos with Suboxone can cause an extreme sedation form, leading to low blood pressure and respiratory depression. The combination can sometimes even cause coma or death. 

Suboxone with Alcohol 

The suboxone treatment centers near me inform me that alcohol consumption is the most common drug abuse case in the US. Both Suboxone and alcohol are considered central nervous system depressants, which means that both substances tend to decrease neuronal firing in the central nervous system. So, consuming alcohol with an opioid drug can be extremely risky and even lethal practice. 

The side-effects associated with both substances intensify when used together. The side-effects include: 





Blurred vision


Profuse sweating

Heart palpitation

A drastic change in blood pressure

More significant potential for myocardial infarction

Decreased motor coordination

Impaired thinking

Respiratory suppression

Decreased blood flow

Comatose state

Suboxone with Cocaine 

According to a suboxone doctor, using cocaine alone poses a significant threat, and when it is combined with substances like opioids, it becomes life-threatening. Cocaine, being a central nervous system stimulator, increases the level of dopamine in the brain. Excess of dopamine due to cocaine can cause serious side effects, including: 

Constricted blood vessels

Dilated pupils

Fluctuation in body temperature

Fluctuation in blood pressure


Abdominal pain


Decreased appetite






Cocaine, when taken with Suboxone, can also lead to a cocaine overdose. Suboxone, which is a mild depressant, fools your body into believing that you can survive a higher dosage of cocaine, although it can’t. The doctors at sublocade treatment centers warn that the combination of cocaine and Suboxone can even lead to heart attack, stroke, and death.  

Rounding off 

The doctors at suboxone treatment near me say that Suboxone is a great medication that has shown positive results in the past years. However, taking it with other harmful substances can have fatal implications. Therefore, the use of the drugs mentioned above is strictly prohibited when the individual is on a course of Suboxone. 

If the individual is also suffering from other issues that require the consumption of medications like benzodiazepines, it is best to discuss everything in detail with the doctors.